Galectin-1 prevents pathological vascular remodeling in atherosclerosis and abdominal aortic aneurysm
نویسندگان
چکیده
Background and Aims: Aim: Pathological vascular remodeling is the underlying cause of main cardiovascular diseases (CVD) including atherosclerosis abdominal aortic aneurysm (AAA). Diminished smooth muscle cell (VSMC) content a key mechanism atherosclerotic plaques AAA instability. We hypothesized that Galectin-1 (Gal-1) could exert protective effects in as previously demonstrated different chronic acute inflammatory diseases.
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ژورنال
عنوان ژورنال: Atherosclerosis
سال: 2021
ISSN: ['0021-9150', '1879-1484']
DOI: https://doi.org/10.1016/j.atherosclerosis.2021.06.282